50例老年喉癌放射治疗疗效分析  

An Analysis of the Treatment of 50 Elderly Patients With Laryngeal Carcinoma

作　　者：傅美娜[1] 方庆亮[1] 王国民[1] 

机构地区：[1]华东医院放疗科,上海200040

出　　处：《中国临床医学》2001年第2期141-142,共2页Chinese Journal of Clinical Medicine

摘　　要：目的 :探讨单纯放疗与术后放疗对老年喉癌的疗效。方法 :回顾性分析 5 0例 6 0岁以上老年喉癌的放射治疗效果。治疗方法 :单纯放疗 (剂量 5 5～ 80Gy)和术后放疗 (剂量 5 0～ 75Gy)。随访率为 92 % ,总的 5年生存率为 46 %。结果 :单纯放疗组(2 8例 )和术后放疗组 (2 2例 )的 5年生存率分别为 39.2 %和 5 4.5 % ,临床I、II、III、IV期的 5年生存率分别为 81.8% ,6 0 % ,38.9% ,和 9.1%。声门上型和声门型的 5年生存率分别为 34.4%和 6 6 .7%。有颈淋巴结转移的预后明显较无颈淋巴结转移的差。结论 :早期声门癌单纯放疗可取得较高的 5年生存率 ,对于II、III期喉癌 ,术后放疗能提高 5年生存率 ,早期诊断及合理的治疗是提高老年喉癌生存期的关键。Objective: To investigate the effect of radiotherapy alone and postoperative radiotherapy in old patients with laryngeal neoplasms. Methods: A retrospective analysis of the treatment of 50 patients more than 60 years old with laryngeal carcinoma was made, 28 patients were treated with radiotherapy alone (dose 55-80Gy),22 with a combination of surgery and postoperative radiotherapy (dose 50-75Gy) The follow-up rate was 92% and five-year survival rate was 46%. Results: The 5-year survival rate for radiotherapy alone group (28 cases) was 39.2%, and postoperative radiotherapy group (22cases) was 54.5%. The 5-year survival rate with stage I?II?III?IV were 81.8%, 60%, 38.9%, and 9.1% respectively. Laryngeal neoplasm of glottis had a higher survival rate than that of superglottis. Patients with lymph-node metastasis had worse survival rate. Conclusion: Early finding and reasonable treatment may be the key points to improve the survival rate of laryngeal carcinoma.

关 键 词：老年人 喉癌 放射治疗 疗效 分析 

分 类 号：R739.65[医药卫生—肿瘤]