高聚生对胃癌患者免疫功能及细胞凋亡的影响  

Effect of Highly Agglutinative Staphylococcin on Immune Function and Cell Apoptosis in Patients with Gastric Carcinoma

作　　者：王强[1] 乔林[1] 王明德[1] 于泽成 朱健[3] 

机构地区：[1]中国医科大学第二临床学院外科,沈阳市110003 [2]沈阳市第一人民医院外科 [3]沈阳市第五人民医院外科

出　　处：《中国肿瘤临床》2001年第4期279-281,共3页Chinese Journal of Clinical Oncology

摘　　要：目的：研究高聚生（Highly Agglutinative Staphylococcin, HAS）对胃癌患者免疫功能和细胞凋亡的影响。方法：胃癌患者30例，随机分为实验组（HAS组）和对照组。检测细胞免疫指标、红细胞免疫指标、体液免疫指标及细胞凋亡的表达。结果：实验组与对照组比较，细胞免疫功能、红细胞免疫功能、细胞凋亡表达均得到明显的增强（P＜0．01或P＜0．05），但体液免疫功能无明显变化（P＞0．05）。结论：应用HAS可以改善胃癌患者的细胞免疫、红细胞免疫功能，促进肿瘤细胞凋亡，提示HAS在胃癌的治疗中有着非常重要的作用。Objective: To study the effect of highly agglutinative staphylococcin (HAS) on the immune function and cell apoptosis in patients with gastric carcinoma． Methods: Thirty patients with gastric carcinoma were randomly divided into experimental group (HAS group) and control group． The parameters of cell immunity, Erythrocyte immunity, , humoral immunity and tumor cell apoptosis expression were determined． Results: There were more significant improvement of cell immunity function, red cell immunity function and cell apoptosis expression than those in control group (P＜0．01 or P＜0．05), but there was no significant difference of humoral immune function between the experimental group and control group (P＞0．05)． Conclusion: HAS can improve cell immunity function and Erythrocyte immunity function and promote tumor cell apoptosis． Therefore, HAS plays a very important role in the treatment of gastric carcinoma．

关 键 词：高聚生 胃癌 细胞免疫 红细胞免疫 细胞凋亡 

分 类 号：R735.2[医药卫生—肿瘤] R730.53[医药卫生—临床医学]