食管癌病因学研究的回顾与展望  

Study on etiology of esophageal carcinoma:retrospect and prospect

作　　者：胡盛平[1] 杨红珊[1] 

机构地区：[1]汕头大学医学院分子生物学中心,广东汕头515031

出　　处：《中国癌症杂志》2001年第2期171-174,共4页China Oncology

基　　金：广东省自然科学基金 (No .0 0 0 819)资助

摘　　要：食管癌是最常见的十大恶性肿瘤之一 ,尤其多发生于中国人。是由环境因素和基因变异相互作用而致的多基因病。本文回顾了食管癌病因学研究的历程 ,并展望了其未来研究方向。Esophageal carcinoma is one of the top frequently occur malignant cancers, especially in Chinese.Studies on esophageal carcinoma have suggested that genetic predisposition, dietary or environmental factors, such as nitrosamine, tobacco smoking, malnutrition, trace element deficieny and fungus toxin could be important in the carcinogenesis of this cancer.

关 键 词：食管癌 亚硝胺 人乳头瘤病毒 癌变相关基因 遗传易感性 病因学 

分 类 号：R735.1[医药卫生—肿瘤] R730.23[医药卫生—临床医学]