含胍基交联聚乙烯醇的合成及其对胆红素吸附性能研究  

Preparation of New Adsorbent for Bilirubin by Immobilizing Guanidine on Crosslinked Polyvinyl Alcohol Gel

作　　者：张克胜[1] 孙君坦[1] 何炳林[1] 

机构地区：[1]南开大学高分子化学研究所

出　　处：《高等学校化学学报》1999年第6期965-968,共4页Chemical Journal of Chinese Universities

基　　金：国家教育部博士点专项基金

摘　　要：通过将胍基固载到交联聚乙烯醇水凝胶上制备了新型亲水性胆红素吸附剂，该类吸附剂对胆红素具有良好的吸附性能和较高的吸附效率．交联聚乙烯醇对胆红素的吸附率随着载体的交联度、离子浓度以及白蛋白与胆红素质量比的增加而降低；A new adsorbent for bilirubin was prepared by immobilizing guanidine on crosslinked polyvinyl alcohol gel. It possesses good adsorption performance for bilirubin both in albuminfree and albumin solutions. The adsorption efficiency increases with the decrease of the crosslinking degree of PVA, the ratio of albumin to bilirubin and ion concentration. The increase of the guanidine amount can improve the adsorption performance.

关 键 词：胍 交联聚乙烯醇 血液灌流 胆红素 吸附剂 吸附性能 高胆红素血 血液净化疗法 

分 类 号：R575[医药卫生—消化系统] R457[医药卫生—内科学]