女性正常及癌变乳腺导管系统铸型的初步研究  

A preliminary study of the resin cast on the normal and cancerous female mammary duct and acinus system

作　　者：李峻[1] 姜军[2] 詹新恩[2] 

机构地区：[1]解放军第458医院普外科,广州510602 [2]解放军第三军医大学西南医院普外科

出　　处：《中华实验外科杂志》2001年第3期236-237,T002,共3页Chinese Journal of Experimental Surgery

摘　　要：目的　研究女性正常及癌变乳腺导管系统的三维结构。方法　收集 2 1例因乳腺癌切除的乳房标本 ,2例尸解的正常乳房标本进行乳腺导管系统铸型研究。结果　每一导管系统均由一输乳管反复分支而成 ,Y型分支占 90 %以上 ,最多为 6分支型 ;女性非哺乳期仍然存在少量腺泡结构 ;乳腺癌浸润导管中断 ,断端边缘参差不齐 ,粗细不均或蚓状扭曲 ,管壁因浸润呈锯齿状或串珠状改变 ,相邻导管明显增生、增多、扩张、不均及扭曲变形 ,呈现癌浸润及相邻导管增生扩张并存的特征。结论　乳腺导管系统铸型法为进一步研究乳腺导管系统的三维形态创造了条件。乳腺增生与乳腺癌共存于同一乳房中 。Objective To investigate the three dimensional structure of normal and cancerous female mammary duct and acinus system. Methods The samples of breast from 21 patients with breast carcinoma and 2 biopsied subjects to study the resin cast on female mammary duct and acinus system. Results Every mammary duct system are made up by many times bifurcated branches of lactiferous duct as a duct tree. 90% of the bifurcation was Y shape, rarely with 6 bifurcated branches. Only a few acini were found on the duct tree of non lactation period. The duct tree which was infiltrated by breast carcinoma showed branches deformity and decreased,break off of the aside duct with irregular borders, outflow of filling materialdue to the cancerous perforation, irregulation and lumbrical tortuosity. The wall of the infiltrated duct showed change of sawtoothlike and toruliform. The neighbor duct tree of some other infiltrated ducts showed obvious hyperplasia, tortuosity, the number of acinus increased and grouped as an irregular lump. It showed a character of carcinoma infiltration and hyperplasia ectasia coexistence. Conclusion The resin cast of mammary duct and acins system creates favorable conditions for studying the three dimensional structure of mammary duct and acinus system. From the morphological view, there may exist some relationship between cystic hyperplasia of breast and carcinoma of breast.

关 键 词：乳腺肿瘤 导管 铸型 三维结构 女性 

分 类 号：R737.9[医药卫生—肿瘤]