北虫草对正己烷所致大鼠损伤的保护作用  

Effect of Cordyceps militaris on the Damage of Rats Induced by n-Hexane

作　　者：沈齐英[1] 陈顺志[2] 

机构地区：[1]北京石油化工学院,102600 [2]锦州医学院,辽宁锦州121001

出　　处：《中药材》2001年第2期112-116,共5页Journal of Chinese Medicinal Materials

摘　　要：采用正己烷急性吸入模型研究北虫草的药效和正己烷的损伤作用。结果表明:北虫草具有抗脂质过氧化作用;正己烷的急性吸入可引起或增强机体活性氧自由基的损伤反应,导致脂质过氧化损伤,这可能是正己烷对机体毒性作用的机制之一。Acutely inhaling n-hexane model was adopted to study the effect of Cordyceps militaris and the damage induced by n-hexane. The results showed that Cordyceps militaris was effective on the resisting lipid peroxidation. The results also showed that acutely inhaling n-hexane could lead to or enhance the damage reaction of oxygen free radicals, which could lead to injure of lipid peroxidation. That may be one of the mechanism of n-hexane toxicity effect on living things.

关 键 词：北虫草 脂质过氧化损伤 正己烷 保护作用 实验研究 

分 类 号：R285.5[医药卫生—中药学]