肺癌脑转移的治疗  

Treatment result for lung cancer with brain metastasis

作　　者：涂明耻[1] 罗汉钰[1] 毛志达[1] 罗伟[1] 潘国英[1] 

机构地区：[1]广州中山医科大学肿瘤医院,510060

出　　处：《中华放射肿瘤学杂志》1996年第1期16-18,共3页Chinese Journal of Radiation Oncology

摘　　要：目的 :探讨影响肺癌脑转移综合治疗的预后因素及提高生存质量的可能性。材料与方法 :1987年 1月～ 1993年 12月间对 117例肺癌脑转移患者行单纯放疗及手术切除加放疗。放疗 (全脑 )剂量2 3～ 4 0 Gy后缩野追加 15～ 2 4 Gy。结果 :手术切除加放疗的中位生存期 9.5个月和 1年生存率 6 2 .5 %显著优于单放组的 5 .7个月和 14 .2 % (P<0 .0 5 )。结论Purpose: To report the treatment result for lung cancer with brain metastasis. Materials and Methods: 117 patients with brain metastases from lung cancers were treated by radiotherapy alone or surgery followed by radiotherapy from January, 1987 to December, 1993. Radiotherapy were given with the dose of 23～40Gy (whole brain irradiation) then followed with 15～24Gy booster. Results: The median survival period and one year survival rate were 9.5 months and 62.5% in surgery plus radiotherapy group and 5.7 months and 14.2% in radiotherapy alone group(P<0.05). Conclusion: Combination therapy of surgery plus radiotherapy is better than radiotherapy alone for brain metastasis from lung cancer.

关 键 词：肺癌 脑转移 放射治疗 生存质量 外科手术 

分 类 号：R734.2[医药卫生—肿瘤] R73－37[医药卫生—临床医学]