甲状腺癌术后残留和复发病灶的放射治疗  

Radiotherapy for residual and recurrent foci after surgery for thyroid gland cancer

作　　者：邱杏仙[1] 王建国[2] 何少琴[1] 王弘士[1] 

机构地区：[1]上海医科大学肿瘤医院放疗科,200032 [2]南京军区第八一医院

出　　处：《中华放射肿瘤学杂志》1996年第1期32-35,共4页Chinese Journal of Radiation Oncology

摘　　要：目的 :分析甲状腺术后残余癌的预后因素及探讨放疗的价值 (包括术后复发 18例 )。材料与方法 :196 5年 1月～ 1987年 12月间对 10 9例 (包括术后复发 18例 )甲状腺术后残余癌患者全部行放射治疗。结果 :其 5 ,10 ,15 ,2 0 ,2 5年生存率分别为 93.6 %、91.7%、88.7%、87.6 %、87.6 % ;无瘤生存率分别为 90 .8%、89.8%、85 .6 %、84 .1%、84 .1%。影响预后因素分析结果显示 :肿瘤的临床分期是影响生存率的决定性因素。年龄、性别、组织学类型、、放射剂量均影响预后。结论 :甲状腺癌术后如有残留需补充放疗 ,不但能增加局部肿瘤的控制率且能提高生存率。最佳剂量为 4 5～ 6 5 Gy。Purpose: To evaluate the effect of radiotherapy and to detect the prognostic factors for residual and recurrent foci after surgery of thyroid gland cancers. Materials and Methods: 109 patients with residual or recurrent foci of thyroid cancers after surgery were treated with radiotherapy. Results:The overall 5-,10-, 15-, 20- and 25- year survival rates were 93.6%, 91.7% , 88.7%, 87.6% and 87.6% and the 5-, 10-, 15-, 20- and 25- year survival rates with no evidence of disease were 90.8%, 89.8% ,85.6%, 84.1% and 84.1%, respectively. The clinical stage was the main factor and patient's age at diagnosis, patient's sex, histopathological types and radiation dose were also the prognostic factors. Conclusion:Radiotherapy is beneficial to residual and recurrent foci after surgery of thyroid cancer. The optimum radiation dose is 45～65 Gy.

关 键 词：甲状腺癌 手术后 残留病灶 复发病灶 放射治疗 预后 

分 类 号：R736.1[医药卫生—肿瘤] R730.55[医药卫生—临床医学]