晚期贲门癌根治性放疗与手术治疗的比较  

Comparison between radical radiotherapy and operation for advanced cardiac carcinoma

作　　者：李宝生[1] 王立英[1] 于安伦[1] 李建彬[1] 于金明[1] 

机构地区：[1]山东省肿瘤防治研究院

出　　处：《中华放射肿瘤学杂志》1997年第4期229-232,共4页Chinese Journal of Radiation Oncology

摘　　要：目的分析比较晚期贲门癌根治性放疗（ＤＴ６０～７０Ｇｙ，６～７周）与手术治疗的疗效。材料与方法１９８５年１月至１９８８年１月间将８２例晚期贲门癌患者随机分为放疗组和手术组进行对比治疗。放疗组４０例，手术组４２例，（手术切除３０例、探查术１２例），放疗剂量ＤＴ６０～７０Ｇｙ，６～７周。结果放射治疗后梗阻症状改善率为９０％，Ｘ线好转率８０％。放疗组与手术切除组１，３，５年生存率分别为８２．５％和６０．０％（Ｐ＜０．０５），２２．５％和０（Ｐ＜０．００１），５％和０（Ｐ＞０．０５），探查组无１例生存１年以上。结论放疗组的疗效明显优于手术组，根治性放射治疗是晚期贲门癌的重要治疗手段。Purpose To compare the treatment results between radical radiotherapy and operation for local advanced cardiac cancer.Materials and Methods 82 patients with local advanced cardiac carcinoma were randomly divided into two groups(radical radiotherapy in 40 and operation in 42 patients) from January 1985 to January 1988.The radiation dose was 60～70Gy/6～7 weeks.Results Improvement of esophageal obstruction on barium meal was 90% in radical radiotherapy.The 1,3,5year survival rates in radiotherapy group and operation group were 82.5% and 60.0%(P<0.05),22.5% and 0% (P<0.001),5% and 0%(P>0.05).Conclusion Radical radiotherapy is much better than operation for patients with local advanced cardiac cancer.

关 键 词：晚期贲门癌 根治性放射治疗 外科手术 比较 

分 类 号：R735.2[医药卫生—肿瘤] R730.5[医药卫生—临床医学]