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作 者:刘晋林[1] 唐桂兰[1] 余顺[1] 刘少君[1] 乔健夫[1]
机构地区:[1]山西省眼科医院,太原030002
出 处:《山东医大基础医学院学报》2001年第2期94-95,共2页
摘 要:目的 :探讨玻璃体与青光眼眼压升高的关系。方法 :用玻璃体切割合并小梁切除治疗疑难青光眼及不同浓度的透明质酸酶注入兔眼玻璃体内改变玻璃体理化状态来降低眼压。结果 :玻璃体切割术后随访0 5~ 4年 ,患者眼压 80 %控制在正常范围 ,自觉症状消失 ,眼局部充血减轻或消失 ,视力多保持原来状态。用药 10~ 2 0~ 30d后 ,兔眼玻璃体粘稠度明显下降 ,眼压从 2 74kPa降至 1 73~ 1 33kPa。结论 :玻璃体切割合并小梁切除及透明质酸酶兔眼玻璃体内注射法均可使眼压下降 ,说明玻璃体对眼内压有一定的影响 ,但手术及实验结果和远期疗效均有待进一步研究。Objective:To research the relationship between the vitreous and the high IOP.Method:Vitrectomy combined with trabeculectomy were used to deal with difficult glaucoma.Hyaluronidase with variety density was injected into rabbits' vitreous body to change the physical and chemical states in order to reduce IOP.Results:Patients with vitrectomy were followed for 0.5~4 years,80% of their IOP were controlled to normal. The symptom was disappeared. Local congestion was relived or absent. Visual acuity had no change.10~20~30 days after used drugs,the viscosity of vitreous was decreased and the IOP was decreased from 2.74kPa to 1.75~1.33kPa.Conclusion:Vitrectomy combined with trabeculectomy and injection of hyaluronidase into rabbit's vitreous can decrease IOP. This result indicate that vitreous can affect IOP, but the long-time effect of the operation and the experiment remain further researching.
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