硫酸锌治疗肝豆状核变性前后肝脾的超声声像图改变  

Ultrasonic Observation of Liver and Spleen in Patients with HLD before and after Zine Sulfate Treatment

作　　者：马晓芹[1] 魏晓兵[2] 苏荣[1] 王英[1] 

机构地区：[1]呼和浩特市内蒙古自治区呼和浩特市第一医院B超室,010020 [2]呼和浩特市内蒙古自治区精神卫生中心,010010

出　　处：《中国医学影像学杂志》2001年第3期184-185,共2页Chinese Journal of Medical Imaging

摘　　要：目的 :观察肝豆状核变性 (HLD)患者服用硫酸锌前后的肝脾声像图变化。材料和方法 :肝豆状核变性患者 8例 ,其中男 2例 ,女 6例 ,年龄 19～ 45岁。超声观察其肝、脾声像图特征 ,给患者长期口服硫酸锌 ,每次剂量 2 0 0～ 40 0mg ,每日 3次。分别于服药后 3个月、6个月、1年 (长期随访 6个月 1次 )复查肝脾超声情况。结果 :肝豆状核变性患者经硫酸锌治疗后其门脉高压征可改善甚至恢复正常 ,肝脏异常回声可有不同程度的改变。结论Purpose: To observe the echographic change of liver and spleen in patients with hepatolenticular degeneration (HLD) before and after taking zine sulfate. Materials and Methods:Eight patients (M2, F6; age 19～45, average age 31) of HLD had ultrasonographic study on their liver and spleen observed before receiving zine sulfate therapy at does of 200～400mg, three time a day. Liver and spleen were examined again after 3, 6 months and 1 year. Results: The symptoms of portal vein hypertension in patients with HLD improved after zine sulfate therapy; the abnormal ultrasonic features of liver had a certain change to different extent. Conclusion: B-mode ultrasonic examination may be used in diagnostic and therapeutic evaluation of HLD.

关 键 词：肝豆状核变性 超声 硫酸锌 治疗 

分 类 号：R742.4[医药卫生—神经病学与精神病学]