旋转式伽玛刀治疗55例听神经瘤分析  

Rotating Gamma Knife for Acoustic Neurianomas (55 Cases)

作　　者：厉民[1] 黄润生[1] 王天华[1] 卢刚[1] 郑新法[1] 黄素文[1] 

机构地区：[1]浙江省人民医院伽玛刀治疗中心,浙江杭州310014

出　　处：《肿瘤学杂志》2001年第1期20-22,共3页Journal of Chinese Oncology

摘　　要：[目的]分析伽玛刀(γ刀)治疗听神经瘤的疗效及适应证 ,并发症发生的原因及预防。[方法]采用OUR -XGD旋转式伽玛刀治疗听神经瘤55例 ,肿瘤平均直径2 9cm ,平均肿瘤边缘剂量14Gy,中心剂量33 6Gy,平均采用的等剂量曲线为48 7 % ,平均等中心点为4 7个 ,随访12～35个月。[结果]肿瘤缩小41 8 % ,肿瘤稳定无增大50 9% ,合计肿瘤生长控制率92 7% ,肿瘤增大7 3%。听神经保护率40 % ,面神经保护率89 8 % ,无死亡病例。[结论]γ刀治疗听神经瘤具有较高的肿瘤生长控制率 ,死亡率极小 ,且可保护颅神经功能 ,是一种有效的治疗方法。To study the effect of gamma knife for acoustic neurianomas.Fifty five patients with acoustic neurianomas treated with OUR-XGD rotating gamma knife.The average of tumor's diameter was 2 9cm.The average tumor peripheral dose was 14 Gy (11Gy～20Gy),the center dose was 35 6Gy (21Gy～40Gy).The mean isodose curve was 48 7%,the average of shots was 4 7 points.Follow_up ranged from 12 to 35 months.Tumors reduced in 23 of 55 patients (41 8%)and stable in 28 of 55 patients (50 9%).The response rate was 92 7%.The tumor progressed in 4 cases of this group.The audition preservation rate was 40%.The facial neuropathic protection rate was 89 8%.No one died.[Conclusion]Gamma knife is an effective treatment for acoustic neurianomas with higher response rate,lower mortality,and less side effect for cranial nerve.

关 键 词：听神经瘤 伽玛刀 放射疗法 治疗 

分 类 号：R739.4[医药卫生—肿瘤]