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机构地区:[1]解放军总医院眼科
出 处:《眼科研究》1998年第1期35-36,共2页Chinese Ophthalmic Research
摘 要:目的研究间接检眼镜光照后试验兔视网膜DNA定量的变化,以评价光照性视网膜损伤。方法13只北京灰兔(26眼),体重2~2.5kg,直接检眼镜检查眼底正常。用双目间接检眼镜为光源,+20.0D透镜聚集在后部视网膜,光照度为390.77mW/cm,光照时间分别为15,30min和1h。结果DNA的水平和光照时间相关。光照后2d和2周,30min组、1h组和对照组比较视网膜DNA含量明显降低,而15min组没有显著变化。结论间接检眼镜光照时间过长可引起视网膜的损害,严重损害为不可逆性感光细胞的损害。ObjectiveTo evaluate light injury to the retina,DNA changes in rabbit retina were quantitatively studied after exposure to indirect ophthalmoscope light.Methods13 Beijing grey rabbits(26 eyes) weighing 22.5 kg,the fundi were examined briefly by direct ophthalmoscope and noted to be normal.Indirect ophthalmoscope with +20.0 D lens was focused on the posterior retina(retinal intensity 390.77 mW/per cm;light injury time 15,30 min and 1 h).ResultsDNA levels in the retina decreased with exposure time of light.2 d and 2 wk after the light exposure,the DNA content in the retina was significantly lower in 30 and 60 min exposure group,compared with the normal control.However 15 min exposure group did not reach a significant level of DNA reduction.ConclusionIndirect ophthalmoscope light may damage retina if the exposure time is long enough.Serious damage is irreversible photoreceptor cell damage.
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