皮质类固醇在真菌性角膜溃疡角膜移植术后的应用  

Administration of corticosteroid after penetrating keratoplasty in fungal corneal ulcer

作　　者：史伟云[1] 谢立信[1] 董晓光[1] 刘敬[1] 李绍伟[1] 褚建[1] 

机构地区：[1]山东省医学科学院眼科研究所

出　　处：《眼科研究》1998年第2期130-132,共3页Chinese Ophthalmic Research

摘　　要：目的对真菌性角膜溃疡行穿透性角膜移植术（ＰＫＰ）后使用皮质类固醇的时间和疗效进行评价。方法８０例真菌性角膜溃疡患者行ＰＫＰ后，随机分成两组，１组术后全身使用皮质类固醇１～２次和２周后开始常规全身使用，另１组术后１个月开始全身使用皮质类固醇，住院期间每日裂隙灯观察前房反应和角膜植片的情况。结果应用皮质类固醇组未见真菌复发率增高，前房反应比对照组明显轻。结论真菌性角膜溃疡行ＰＫＰ术后，适当掌握使用皮质类固醇的时间和剂量，对减轻术眼炎症反应，减少术后排斥率非常有效。ObjectiveTo evaluate the effectiveness and the time of the administration of corticosteroid after penetrating keratoplasty(PKP) in management of fungal corneal ulcer.Methods80 cases of fungal corneal ulcer were separated into two groups.The effectiveness of corticosteroid administered at different time and the relapse of fungal corneal ulcer were observed.ResultsThe rate of relapse of fungal coneal ulcer didnt increase and inflammatory reaction in anterior chamber was less serious than control group.ConclusionIt’s very effective in alleviating the inflammatory reaction and in reducing the reject rate if corticosteroid is administered with correct dosage at correct time.

关 键 词：真菌性角膜溃疡 皮质类固醇 穿透性角膜移植 PKP 

分 类 号：R772.21[医药卫生—眼科] R779.65[医药卫生—临床医学]