口腔颌面部肿瘤患者血清中总唾液酸及脂结合唾液酸的测定  

Assay of Total Sialic Acid and Lipid Bound Sialic Acid in Sera of Patients with Oral and Maxillofacial Tumor

作　　者：周磊[1] 毛祖彝[1] 王模堂[1] 温玉明[1] 

机构地区：[1]华西医科大学口腔医学院

出　　处：《华西口腔医学杂志》1991年第2期98-101,共4页West China Journal of Stomatology

摘　　要：用改良 Aminoff 法和改良 Katopodis 法对179例口腔颔面部肿瘤患者血清唾液酸(TSA)和脂结合唾液酸(LSA)进行了测定。结果显示口腔鳞癌和涎腺恶性肿瘤患者 TSA 和 LSA 水平高于正常;术后复发组高于无复发组及正常组;血清 TSA 及 LSA 水平与肿瘤的严重程度有明显关系;手术后血清 TSA 及 LSA 明显下降。采用71mg/dl和20mg/dl分别作为 TSA 和 LSA 区分恶性与非恶性肿瘤的鉴别参考值时,口腔鳞癌和涎腺恶性肿瘤组的阳性检出率,TSA 分别为37%(23/63)和67%(14/21);LSA 分别为70%(44/63)和57%(12/21)。In this paper,TSA was assayed with modified method of Aminoff and LSA wasassayed with modified method of Katopodis and Stock.Significantly elevated TSA and LSA concentrations were found in the patients withcarcinoma of oral and salivary glands as compared to normal controls.Significantly elevated TSA and LSA concentrations were also found in the patientswith recurrent cancer as compared to normal controls and operated patients who had noevidence of residual tumor at the time of blood sampling.The test showed that serum TSA and LSA levels were significantly related to tumorstage and a significantly decrease could be observed in the levels of serum TSA and LSAwhen the patients had all known primary carcinoma been excised.

关 键 词：颌面部肿瘤 唾液酸 测定 

分 类 号：R739.810.4[医药卫生—肿瘤]