Ⅲ期子宫内膜癌预后的多因素分析  

Multi-factor Analysis on Prognosis of Stage Ⅲ Endometrial Carcinoma

作　　者：贺国强[1] 雷立芳[1] 陈亦乐[2] 

机构地区：[1]湖南医学高等专科学校,中国湖南长沙410006 [2]湖南省肿瘤医院,中国湖南长沙410006

出　　处：《湖南医学》2001年第3期166-167,共2页Hunan Medical Journal

摘　　要：目的探讨Ⅲ期子宫内膜癌的治疗方法等多种因素与生存时间的关系 ,为临床处理提供更合适的方案。方法采用COX模型回归分析 2 4例Ⅲ期子宫内膜癌的治疗方法、淋巴结转移、病理学特征、年龄、肌浸深度及宫腔深度 6个预后因素对生存时间的影响。结果治疗方法与淋巴结转移对生存率影响最大 ,肌浸深度与宫腔大小对生存率影响最小 ,年龄与生存率呈负相关。结论Ⅲ期子宫内膜癌的治疗方式以综合放疗加广泛子宫切除加盆腔淋巴结清扫术为优 ;年轻患者辅以化疗或激素治疗能否防止远处转移及提高生存率有待研究。ObjectiveTo investigate the relationships between multiple factors (such as methods of treatment etc.) and the survival time in stage Ⅲ endometrial carcinoma with our aim at providing more suitable project for its clinical management. Methods Adopting COX pattern regression analysis, effects of 6 prognostic factors on the survival time were studied in 24 cases of stage Ⅲ endometrial carcinoma. Factors studied included methods of treatment,lymph node metastasis, pathological features, age, myoinvasive depth and uterine size. ResultsThe methods of treatment and lymph node metastasis showed most distinct effects on the survival rate of stage Ⅲ endometrial carcinoma, while myoinvasive depth and uterine size exerted the least influence. Negative correlation existed between the age and survival rate. Conclusions It is better to use combinative measures of radical hysterectomy, pelvic lymphadenectomy and radiotherapy in the treatment for stage Ⅲ endometrial carcinoma.It still needs further investigation whether these measures supplemented with chemotherapy and hormone therapy can prevent the distant metastasis and improve survival rate in younger patients. [

关 键 词：子宫内膜肿瘤 子宫内膜癌 多因素分析 预后 

分 类 号：R737.33[医药卫生—肿瘤]