半合成红霉素研究进展  

Recent Progress in Studies on Semi synthetic Erythromycin

作　　者：李兴发[1] 尤启冬[1] 

机构地区：[1]中国药科大学药化教研室,江苏南京210009

出　　处：《药学进展》2001年第3期138-141,共4页Progress in Pharmaceutical Sciences

摘　　要：综述红霉素结构修饰和构效关系研究的新进展 ,介绍其新衍生物 ,特别是以 Ketolides为代表的内酯环 C-3位修饰衍生物 。The research progress of Erythromycin in chemical modification and structure activity relationship was reviewed. The marketing products,new derivatives and new products in R&D ,particularly the C 3 modified derivatives represented by Ketolides were also introduced.

关 键 词：红霉素 结构修饰 KETOLIDES 构效关系 

分 类 号：R914[医药卫生—药物化学]