伽玛刀剂量计划系统照射容积和靶区容积的相关性比较  

Relationship Comparative Study Between Prescription Volume and Target Volume in Gamma Knife Dose Planning

作　　者：袁士毅[1] 潘力[1] 张南[1] 

机构地区：[1]复旦大学附属华山医院-上海伽玛医院神经外科,上海200233

出　　处：《复旦学报（医学版）》2001年第3期227-229,共3页Fudan University Journal of Medical Sciences

摘　　要：目的　通过对伽玛刀治疗计划中照射容积和靶区容积的差异比较 ,进行剂量计划的优选 ,以准确设定照射范围 ,减少治疗后的并发症。方法　将 86 0例病人的靶区容积、照射容积及靶区 (照射 )容积直方图进行比较和统计分析。结果　中位数百分比合格率最高为脑膜瘤 ,其次为垂体瘤 ,听神经瘤和AVM ,最低为淋巴瘤。结论　进一步缩小靶区容积和照射容积差异 ,对提高伽玛刀剂量计划设计的最优化。Purpose To optimize the individual Gamma Knife dose planning by the comparative study between prescription volume and target volume. Methods The target volume,presciption volume and their histogram of eight hundred and sixty patients had been compared and statistically analysed. Results The median ratio of prescription volume and target volume had been detailed.That of meningioma ranked first.Pituitary adenoma,acoustic neurinoma and AVM ranked second and third.That of lymphoma was the lowes t.Three hundred and eighty five cases had been followed up.Lesions of 154 cases regressed and disappeared,of 192 cases had partial shrinkage(>50%),of 27 cases (<50%)and of 13cases enlarged. Conclusions To abate the differences between prescription volume and target volume may improve the optimization of dose planning and decreased the complications after radiosurgery.

关 键 词：立体定向放射外科 照射容积 脑肿瘤 伽玛刀剂量计划系统 靶区容积 

分 类 号：R739.41[医药卫生—肿瘤]