绍兴鸭卵巢各级卵泡中WT1 mRNA的表达  

Expression Pattern of WT1 mRNA in Shaoxing Duck Ovarian Follicles

作　　者：傅衍[1] 牛冬[1] 阮晖[2] 陈功[1] 余旭平[1] 杨培新[1] 

机构地区：[1]浙江大学动物科学学院,杭州310029 [2]浙江大学农业工程与食品科学学院,杭州310029

出　　处：《中国生物化学与分子生物学报》2001年第4期533-536,共4页Chinese Journal of Biochemistry and Molecular Biology

基　　金：国家自然科学基金资助课题 (No .3990 0 10 6 )&&

摘　　要：WT1(Wilms’ tumor suppressor)is a zinc finger protein with transcriptional repressor activity on several growth factor and growth factor receptor genes.The very sensitive quantitative competitive RT PCR was used to investigate the expression of mRNA for WT1 in the developing ovarian follicles of Shaoxing duck.The results revealed that all follicles showed the expression of mRNA for WT1.The WT1 mRNA was highly expressed only in the small preantral follicles,and with far lower expression in the large follclies.The results suggest that WT1 may play an important role in early follicular development possibly by suppressing the activities of factors that stimulate follicle growth and differentiation in immature follicles.WT1(Wilms' tumor suppressor)is a zinc finger protein with transcriptional repressor activity on several growth factor and growth factor receptor genes.The very sensitive quantitative competitive RT PCR was used to investigate the expression of mRNA for WT1 in the developing ovarian follicles of Shaoxing duck.The results revealed that all follicles showed the expression of mRNA for WT1.The WT1 mRNA was highly expressed only in the small preantral follicles,and with far lower expression in the large follclies.The results suggest that WT1 may play an important role in early follicular development possibly by suppressing the activities of factors that stimulate follicle growth and differentiation in immature follicles.

关 键 词：绍兴鸭 卵巢卵泡 WT1 MRNA 表达 

分 类 号：S834[农业科学—畜牧学]