应用微波辐射技术合成尼群地平  

Synthesis of Nefedipine by Wicrowave Treatment

作　　者：屠树江[1] 马恒俊[1] 邓旭[1] 姚昌盛[1] 

机构地区：[1]徐州师范大学化学系,徐州221009

出　　处：《应用化学》2001年第6期507-508,共2页Chinese Journal of Applied Chemistry

摘　　要：The Nefedipine has been synthesized by reaction of m-nitrobenzaldehyde , ethyl acetoactate and ammomiun acetate under microwave irradiation without solvent. The reaction is completed in 4 min with 82% yield.The Nefedipine has been synthesized by reaction of m-nitrobenzaldehyde , ethyl acetoactate and ammomiun acetate under microwave irradiation without solvent. The reaction is completed in 4 min with 82% yield.

关 键 词：尼群地平 微波辐射 合成 钙离子通道调节剂 1 4-二氢吡啶 

分 类 号：TQ463.54[化学工程—制药化工]