双苄基异喹啉类生物碱汉防己乙素的二维核磁共振谱  

2DNMR SPECTRA OF BISBENZYLISOQUINOLINE ALKALOID FANGCHINOLINE

作　　者：杨劲松[1] 张强[1] 周游[1] 苏甫[1] 王锋鹏[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《华西药学杂志》2001年第3期161-164,共4页West China Journal of Pharmaceutical Sciences

摘　　要：目的：系统研究汉防己乙素的核磁共振谱。方法：应用１Ｄ（１Ｈ，１３Ｃ）和２Ｄ（１Ｈ－１Ｈ ＣＯＳＹ，ＨＭＱＣ，ＨＭＢＣ）ＮＭＲ技术。结果：首次指定了汉防己乙素 ＮＭＲ谱中所有１Ｈ（１３Ｃ）信号的化学位移。结论：２Ｄ ＮＭＲ技术是解决汉防己乙素１Ｈ（１３Ｃ）信号峰归属的关键。OBJECTIVE: To study systematically on 1H and 13C NMR spectra of fangchinoline. MEIHODS: 1D(1H,13C NMR)and 2D(1H-1H COSY, HMQC, HMBC) NMR techniques were used. RESULTS: Both of the 1H and 13C chemical shifts of fangchinoline were assigned for the first time. CON- CLUSION: 2DNMR techniques are the key metheds to the NMR assignment of fangchinoline.

关 键 词：双苄基异喹啉类生物碱 汉防己乙素 二维核磁共振谱 

分 类 号：R917[医药卫生—药物分析学]