胰腺癌内分泌功能改变的诊断意义  

The Diagnostic Value of Pancreatic Endocrine′s Change for Adenocarcinoma of Pancreas

作　　者：徐晓红[1] 唐秀芬[1] 陆以霞[1] 

机构地区：[1]黑龙江省医院消化内科,150036

出　　处：《中国误诊学杂志》2001年第8期1130-1133,共4页Chinese Journal of Misdiagnostics

摘　　要：目的　探讨胰腺内分泌功能改变对胰腺癌的诊断意义。方法　选择胰腺癌、慢性胰腺炎及健康受试者各30例进行口服糖耐量试验 (OGTT)和胰岛素释放试验 (IRT) ,胰高血糖素测定 (GL) ,分别绘制动态曲线 ,判定 OGTT-IRT曲线类型 ,GL 的高低。结果　胰腺癌组多数有糖耐量异常及继发临床糖尿病 ,胰岛素分泌多数增高 ,慢性胰腺炎组可发生糖耐量异常者曲线类型多不相同 ,胰岛素分泌减少 ,二者在胰高血糖素方面改变无显著差异。结论　OGTT- IRT在对胰癌与慢性胰腺炎的鉴别诊断中具有重要辅助诊断价值。Objective To study the diagnostic value of pancreatic endocrine′s change for adenocarcinoma of pancreas.Methods 30 cases of adenocarcinoma of pancreas and 30 cases of chronic pancreatitis controls were tested by OGTT,IRT and pancreatic glucagons,then draw development curved line and determine the type of them.Results It show that most cases in the group of adenocarcinoma of pancreas has glucose tolerance abnormality and secondary clinical diabetic mellitus,with insulin secretion increased.The glucose tolerance abnormality of chronic pancreatitis was differet from the former,with insulin secretion decreased.They both had no significant difference in pancreatic glucagons.Conclusion OGTT-IRT has important accessory diagnostic value for the differential diagnosis of adenocarcinoma of pancreas and chronic pancreatitis.

关 键 词：胰腺癌 糖耐量试验 胰岛释放试验 胰高血糖素 诊断 

分 类 号：R735.904[医药卫生—肿瘤]