脑梗塞患者颈动脉粥样硬化斑块与血脂变化的研究  

A Study of Carotid Atherosclerotic Plaques and Serum Lipoproteins in the Patients with Cerebral Infarction

作　　者：季建中[1] 李华 候惠鸣[1] 翟江[1] 陈宗羡[1] 

机构地区：[1]河北省张家口医学院第二附属医院神经内科,075100 [2]河北省张家口市第二人民医院,075000

出　　处：《中国误诊学杂志》2001年第8期1147-1148,共2页Chinese Journal of Misdiagnostics

摘　　要：目的　研究脑梗塞患者颈动脉粥样硬化斑块与血清氧化低密度脂蛋白 (OX- L DL)、脂蛋白 a(L Pa)的关系。方法　采用酶联吸附试验测定 116例脑梗塞患者血清 OX- L DL、L Pa,再根据颈动脉超声多普乐检查结果 ,将患者分为斑块组、无斑块组 ,对比分析。结果　斑块组 OX- L DL高于无斑块组 ,而 L Pa显著低于无斑块组。结论　OX- L DL增高是促进斑块形成的重要因素 ,颈动脉粥样硬化斑块形成以后 L Pa反而下降。Objective To study the relationship between carotid atherosclerotic plaques with serum oxidized low dencity lipoprotein(OX-LD) and lipoprotein a(LPa) in the patients with cerebral infarction.Methods To measure serum oxidized low density lipoprotein and lipoprotein(a) levels with an enzyme-linked immunosorbent assay in 116 patients with cerebral infarction.Then the patients with cerebral infarction were divided into the group with plaques and the group without plaques according to the rtresults of carotid ultrasound.Results The serum oxidized low density lipoprotein levels in the group with plaques were higher than the group without plaques,but the serum lipoprotein(a)in the group with plaques were lower than the group without plaques.Conclusion The high serum oxidized low density lipoprotein level is an important factor of carotid atherosclerotic plaques fromation.The serum lipoprotein(a) level fall after the carotid atherosclerotic plaques have formed.

关 键 词：脑梗塞 颈动脉粥样硬化斑块 氧化低密度脂蛋白 脂蛋白A 

分 类 号：R743.330.2[医药卫生—神经病学与精神病学]