超声引导下经皮射频毁损肝癌疗效分析及安全性评价  

Percutaneous radio frequency ablation of liver cancer guided by ultrasonography

作　　者：袁爱力[1] 张振书[1] 侯淑琴[1] 郭文[1] 崔生达[1] 林焕建[1] 姜泊[1] 白岚[1] 蓝琳[1] 

机构地区：[1]第一军医大学南方医院消化内科,全军消化疾病研究所,广州510515

出　　处：《中华消化杂志》2001年第5期281-283,共3页Chinese Journal of Digestion

摘　　要：目的　探讨经皮射频 (radiofrequency ,RF)治疗对肝癌的疗效 ,并对其适应证、禁忌证及不良反应进行评价。方法　 15 4例原发性或继发性肝癌患者 ,肿块平均直径为 7.0 7cm。采用RF 2 0 0 0TM射频治疗仪 ,于B超引导下进行射频治疗 ,观察疗效及并发症。结果　 15 4例患者共行 182次治疗 ,平均每例治疗 1.18次 ,每次治疗 5 .74点。治疗后症状有改善 ,AFP平均浓度由治疗前的 15 5 3 .6 8ng/ml下降至 883 .70ng/ml。肿块缩小率为 5 6 .8%。无致死性或严重致残性的并发症发生。结论　经皮射频治疗肝癌方法简单 ,安全有效。大肝癌可分次治疗 ,但需与其他介入治疗等联合应用以提高疗效。Objective To investigate the effects of percutaneous radio frequency ablation of liver cancer, and evaluate the indications, contraindications, and side effects. Methods One hundred and fifty four patients with hepatocellular carcinoma or metastases liver cancer, with the average diameter of the tumours 7.07 cm were treated with by radio frequency RF 2000TM instrument, the results were evaluated. Results Average theraputic time was 1.18 times, the theraputic point was 5.74. The symptoms were improved after therapy, and the average concentration of AFP was droped from 1 553.68 ng/ml to 883.70 ng/ml. The percentage of tumour reduction was 56.8%. There were no serious complications observed. Conclusion Percutaneous radio frequency ablation of liver cancer is a simple, safe and effective method. For larger liver cancer several times action will be needed, or other intervantion therapy is added to enhance effectiveness.

关 键 词：射频治疗 肝癌 超声引导 治疗 疗效 安全性 

分 类 号：R735.7[医药卫生—肿瘤] R730.5[医药卫生—临床医学]