应用Cox模型分析胃癌患者切除术后的预后因素  

FACTORS INFLUENCING SURVIVAL IN PATIENT WITH GASTRIC CARCINOMA AFTER RESECTION: ANALYSIS BY Cox'S PROPORTIONAL HAZARD MODEL

作　　者：胡建昆[1] 陈志新[1] 肖凤鸣[1] 陈佳平[1] 王文静[2] 彭德恕[1] 

机构地区：[1]华西医科大学附属第一医院普外科,成都610041 [2]华西医科大学附属第四医院统计教研室,成都610041

出　　处：《中国普外基础与临床杂志》2001年第3期162-163,共2页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探讨影响胃癌切除术患者的预后因素。方法对华西医科大学附属第一医院１９８８年１月至１９９３年４月间４２８例胃癌切除患者中资料完整的３４３例进行单因素及多因素Ｃｏｘ模型分析。结果腹膜转移、Ｂｏｒｒｍａｎｎ分型、手术方式、肝转移、肿瘤大小、病变部位、淋巴结转移、年龄等为影响胃癌患者切除术后生存的８个主要因素。结论Ｃｏｘ模型能准确分析胃癌患者切除术后的预后因素。Objective To clarify the most important factors affecting the survival of patient with gastric carcinoma. Methods 428 cases of resected gastric carcinoma were studied by using univariate analyses and multivariate regression analyses. Results The most significant factors influencing survival of these patients were peritoneal dissemination. Borrmann classification, type of operation, hepatic metastasis, size of tumor, location, lymph node metastasis and age. Conclusion The factors influencing survival in patient with gastric carcinoma after resection can be correctly analyzed by cox's proportional hazard model.

关 键 词：胃肿瘤 COX模型 统计学 预后 

分 类 号：R735.2[医药卫生—肿瘤]