龈下菌斑中肽酶活性和龈沟液中天冬氨酸转氨酶水平相关性的研究  

The study of the correlation between peptidase activity in subgingival plaque and aspartate aminotransferase in gingival crevicular fluid

作　　者：张贤华[1] 吴织芬[1] 

机构地区：[1]第四军医大学口腔医学院,西安710032

出　　处：《现代口腔医学杂志》2001年第4期271-272,共2页Journal of Modern Stomatology

摘　　要：目的　探讨成人牙周炎龈下菌斑中肽酶活性和龈沟液中天冬氨酸转氨酶水平的相关性。方法　利用Periocheck椅旁快速检测 60例成人牙周炎患者共 72个位点、1 5例健康对照 1 5个位点龈下菌斑中肽酶活性 ,同时用全自动生化分析仪检测龈沟液中天冬氨酸转氨酶水平。结果　成人牙周炎位点肽酶活性、天冬氨酸转氨酶水平显著高于健康对照组 ,并与探诊深度、附着丧失、牙龈指数呈正相关关系 ,同时二者之间具有一定的相关性。结论　龈下菌斑中肽酶活性和龈沟液中天冬氨酸转氨酶水平相关 ,反映牙周炎的严重程度 ,可用于牙周炎的监测。Objective To observe the possible correlation between the peptidase activity in subgingival plaque and aspartate aminotransferase (AST) in gingival crevicular fluid (GCF) in adult periodontitis and evaluate the diagnostic value of two enzymes for the activity of periodontitis.Methods To measure 72 sites in 60 adult periodontitis patients peptidase activity in subgingival plaque by Periocheck chair-side rapid diagnosis and AST levels in GCF by automatic analysis.Results Peptidase activity and AST levels were much higher in adult periodontitis patients than those in healthy controls.The peptidase activity and AST level significantly correlated with clinical parameters such as PD?AL and GI.Peptidase activity and AST levels were found to have significantly positive correlation with each other.Conclusion These results indicate that peptidase activity in subgingival plaque and AST level in GCF correlate with each other and might be considered as potential markers for the severity of periodontitis.

关 键 词：肽酶 椅旁快速检测 天冬氨酸转氨酶 牙周炎 

分 类 号：R780.2[医药卫生—口腔医学]