帕米磷酸二钠治疗多发性骨髓瘤的溶骨性病变的临床观察  

The clinical observation of the therapeutic effectiveness of Pamidronat edisodium for osteolytic lesion induced by mutiple myeloma

作　　者：左孟华[1] 姜振宇[1] 刘冬莉 

机构地区：[1]吉林大学第一医院,吉林长春130021 [2]长春市南关区曙光医院,吉林长春130000

出　　处：《吉林医学》2001年第4期215-216,共2页Jilin Medical Journal

摘　　要：目的 :探讨帕米磷酸二钠治疗多发性骨髓瘤的溶骨性病变的疗效。方法 :在 35例患者中以帕米磷酸二钠和密钙息为对照药进行对比研究。结果 :帕米磷酸二钠对多发性骨髓瘤的溶骨性病变的有效率高于密钙息 (P <0 0 1)。结论Objective To study the therapeutic effectiveness o f Pamidronate disodium for osteolytic lesion induced by mutiple myeloma.Me thod To compare the therapeutic effectiveness of Pamidronate disodium and that of Miacalcic used as control group in 35 patients.Results t he effective rate of Pamidronate disodium for osteolytic lesion induced by mutip le myeloma is significantly higher than that of Miacalcic( P <0 01).Conclusions Better response can be gotten when Pamindronate disodium i s used in reducing the incidence of skeletal events and its complications induce d by the tumor.

关 键 词：帕米磷酸二钠 溶骨性病变 高血钙 多发性骨髓瘤 治疗 疗效 

分 类 号：R733.7[医药卫生—肿瘤]