经保留导管区域性动脉灌注化疗胰腺癌的疗效观察  

The Observation on the Chemical Theraputic Effect of Pancreatic Carcinoma by theRegional Arterial Infusion and Catheter Mantained

作　　者：文华长[1] 文永均[2] 李佳容[2] 许国辉[1] 陈学浩[1] 李政文[1] 

机构地区：[1]四川省肿瘤医院影像科,四川成都610041 [2]四川省肿瘤医院供应室,四川成都610041

出　　处：《实用放射学杂志》2001年第7期533-535,共3页Journal of Practical Radiology

摘　　要：目的　探讨经保留导管区域性动脉灌注化疗胰腺癌的疗效及价值。方法　本文 15例胰腺癌患者 ,采用Seldinger技术经股动脉穿刺插管后 ,将导管先端插进腹腔动脉干 ,然后把导管的体外段盘曲、固定在腹股沟韧带上方。术毕采用ADF方案经保留导管行腹腔动脉干区域性灌注化疗。结果　本文 15例胰腺患者中 ,黄疸完全消退者 8例 ,减轻者 4例 ,总有效率 80 % ( 12 /15 ) ;腹痛症状消失者 9例 ,减轻者 6例。食欲改善及体重有增加者共 12例。生存期 :1,2 ,3年分别为 9例、5例和 3例。结论　本文结果表明 ,对胰腺癌的治疗 。Objective To study the chemincal theraputic effect and value of pancreatic carcinoma by regional arterial infusion and catheter mantained.Methods The catheterization using Selolinger by transfemoral artery puncture were performed in fifteen patients.The ends of catheters were inserted into coeliac trunk.The segments of catheters out of body were circled and fixed above inguinal ligment.After operation,the chemotherapy transcatheters were performed with ADF projects.Results Of 15 cases,jaundice was disappeared in 8 cases,slight ened in 4 cases,the total effective rate was 80%(12/15).Abdominal pain was disappeared in 9 cases and slight ened in 6 cases Appetite and weight of patients were improved and increased in 12 cases.The 1,2 and 3 year survival rates were 60%(9/15),33.3%(5/15),20%(3/15).Conclusion The chemotherapy by the regional arterial infusion is superior to traditonal venous chemotherapy for pancreatic carcinoma.

关 键 词：胰腺癌 化疗 介入放射学 经保留导管区域性动脉灌注化疗 ADF方案 X线解剖学 

分 类 号：R735.9[医药卫生—肿瘤] R813[医药卫生—临床医学]