砷致皮肤癌及其电化疗疗效观察  

Treatment of electrochemotherapy in arsenicum-induced skin cancer

作　　者：岑笃才[1] 张爱华[2] 敖飞[1] 任渝江[1] 刘忠义[1] 李陆[1] 

机构地区：[1]贵州解放军44医院肿瘤科,贵州贵阳550009 [2]贵阳医学院预防医学系,贵州贵阳550002

出　　处：《中国地方病学杂志》2001年第5期381-382,共2页Chinese Jouranl of Endemiology

基　　金：国家自然科学基金资助 ( 396 6 0 0 70 )

摘　　要：目的　探讨使用电化疗治疗砷致皮肤癌的临床疗效及应用价值。方法　在中、重度砷中毒患者中 ,选择 6 2例患者进行活检 ,病理检查确诊为砷性皮肤癌 15例 ,占 2 4.2 %。其中 Bowen's病 12例 ,鳞状细胞癌 2例 ,基底细胞癌 1例。均采用电化疗治疗的方式 ,治疗后 1年评价疗效。结果　完全缓解 14例 ,部分缓解 1例 ,缓解率为 10 0 % ,2年后随访疗效为 93.3%。结论　燃煤砷致皮肤癌的电化学治疗 ,方法简便 ,安全且费用较低 ,疗效高 。Objective To investigate clinical treatment of electrochemotherapy in arsenicum-induced skin cancer.Methods The biopsy of skin was performed in 62 cases of patients with chronic arsenid poisoning who had received a physical examination and 15 skin cancers were found pathologically,from treatment with electrochemotheraty alone.Results CR 14 cases,PR 1 cases.The total effective rate was 100%.Conclusions The electrochemoheropy is safe,simple,cheaper and exhilarant in the treatment of arsenicum-induced skin cancer and it is advisable in countryside polluted by arsenicum.

关 键 词：皮肤癌 电化学治疗 贵州 CAP 慢性砷中毒 地方性砷中毒 

分 类 号：R739.5[医药卫生—肿瘤] R599.9[医药卫生—临床医学]