术中超声微波介入治疗肝癌的临床研究  

Clinical Research on Interventional Microwave Coagulation Guided by Intraoperative Ultrasonographic Localization in the Treatment of Advanced Liver Cancer

作　　者：何文[1] 杜洪涛[1] 徐利群[1] 姜晓红[1] 冯宝华[1] 郑永才[2] 陈先祥[2] 

机构地区：[1]首都医科大学附属北京朝阳医院超声科,北京市100020 [2]郧阳医学院附属人民医院

出　　处：《中国超声医学杂志》2001年第9期688-690,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 :探讨术中超声微波介入治疗肝癌的临床价值。方法 :2 0例肝癌患者 ,大小 5～ 15 cm,近肝门或浸及胆囊 ,或位于右后上叶向外生长 ,左右叶分布。术中暴露肿瘤 ,或超声定位 ,长时间低功率多点多部位微波凝固 ,暂时阻断血流 ,凝固肿瘤滋养血管 ;难以全部切除的大肿瘤 ,部分切除减瘤 ,残存的肿瘤微波凝固。结果 :术中肿瘤颜色变暗 ,变瘪 ,局部血管栓塞。复查坏死区明显加大 ,肿瘤缩小 ,肿瘤内血流减少或消失。 CT检查肿瘤缩小 ,无强化。活检完全坏死。随访 3～ 2 8月 ,16例存活。结论 :术中微波直观 ,易从不同方向进针 ,克服了经腹微波治疗的不足 ,坏死区大 。Objective:To evaluate the clinical value of interventional microwave coagulation therapy for advanced liver cancer guided by US localization during operation.Methods:The ultrasound microwave therapy(UMC 1)equipment was utilized to treat 20 patients with advanced liver cancer during operation,by multistage,multipoint and longtime segmental coagulation from inferior to superior,or cutting off blood flows of the liver cancer at short period of time,so as to coagulate tumor vasculature.Big tumors unable to be completely removed were partially resected,and the remaining part of the neoplasms were treated with microwave coagulation.Results:Sixteen patients remained alive in 3～28 months followed up after the treatment,all lesions were decreased in size and the blood flows in nodules disappeared.Repeated biopsy in 11 patients showed complete tumor necrosis.There was no enhancement in the tumors by enhanced CT scans.Decrease in conteur size and thrombi in vessels were also visualizd in CT.Conclusions:This method has the advantages over direct visualization to choose different angles for puncture and curing large necrotic areas in hepatic tumors with percutaneous interventional microwave coagulation guided by US only one time.

关 键 词：术中超声 介入性微波治疗 肝癌 临床研究 

分 类 号：R735.7[医药卫生—肿瘤] R730.55[医药卫生—临床医学]