中心性浆液性脉络膜视网膜病变发病机理探讨  

Research on genetic mechanism of central serous choroidretinopathy

作　　者：朱赛林[1] 王煊[1] 王润生[1] 俞江[1] 李守延[1] 

机构地区：[1]西安市第四医院眼科西安市眼底病研究所,西安710004

出　　处：《西安医科大学学报》2001年第4期385-386,395,共3页Journal of Xi'an Medical University(Chinese)

基　　金：陕西省卫生厅资助课题 97 0 2 4

摘　　要：目的　研究中心性浆液性脉络膜视网膜病变 (CSC)始发病变在视网膜色素上皮 (RPE)还是在脉络膜毛细血管 (CC) ,以探讨其发病机理。方法　对 81例 86只眼CSC患者应用荧光眼底血管造影 (FFA)和吲哚菁绿血管造影 (ICGA)结合临床经过进行分析。结果　首次造影者RPE病变处与之相对应部位的CC均有病变 ,且范围较大 ;病变发展到一定时期 ,症状存在时CC病变依然存在 ,但RPE的病变部位已恢复正常。待症状消失时CC病变及RPE病变全部消失 ,ICGA、FFA均正常。结论　CC功能的变化与CSC转归相一致 ,RPE的病变在CSC的某一阶段出现 ,证明CSC的始发病变由CC功能紊乱所致 ,RPE病变是继发于CC病变。ObjectiveTo study central serous choroidretinopathy (CSC) originally deriving from retina l pigmental epithelium or choroidal capillary (CC).Methods Eightyone patients (86 eyes) with CSC were performed by fundus fluorescein ang iography (FFA) and indocyanine green agiography (ICGA).ResultsBoth retinal pigmental epithelium and choroidal capillaries pathy were found dur ing first FFA and ICGA. When the pathy developed one stage,both of the symptom o f CSC and CC's pathy still existed, but the pathy of RPE returned.FFA an d ICGA showed that the symptom of CC disappeared, while both the pathy CC and RP E returned. ConclusionThe change of CC are accord with the cha nge of CSC. The results show that CSC comes from CC dysfunction firstly,PPE's pa thy seconds CC.

关 键 词：中心性浆液性脉络膜视网膜病变 视网膜色素上皮 脉络膜毛细血管 眼底 眼色素层 血管造影 

分 类 号：R773.4[医药卫生—眼科]