HA,LN,PⅢP及Ⅳ-C测定对慢性肝炎和肝硬化的诊断价值  

CLINICAL EVALUATION OF DETECTING HA,LN, PⅢP AND Ⅳ-C IN CHRONIC HEPATITIS AND HEPATIC CIRRHOSIS

作　　者：许开利[1] 马红[1] 魏涛[2] 

机构地区：[1]青岛大学医学院松山医院检验科,青岛266021 [2]青岛市市立医院放免中心

出　　处：《青岛大学医学院学报》2001年第2期137-137,共1页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：①目的　探讨血清透明质酸 (HA)、层黏蛋白 (LN)、Ⅲ型胶原前肽 (PⅢP)、Ⅳ型胶原 (Ⅳ C)在慢性肝炎和肝硬化中的诊断价值。②方法　应用放免法测定慢性肝炎、肝硬化病人血清HA ,LN ,PⅢP ,Ⅳ C的含量 ,同时与正常对照组进行比较。③结果　重度肝炎、肝硬化病人的血清HA ,LN ,PⅢP ,Ⅳ C含量与对照组比较均有显著差异 (F =32 .4～ 113.9,q =6 .2 0 8～ 2 3.12 5 ,P <0 .0 1)。 ④结论　血清HA ,LN ,PⅢP及Ⅳ C的测定 。Objective To study the value of HA, LN, PⅢP and Ⅳ C in the diagnosis of chronic hepatitis and hepatic cirrhosis. Methods Serum HA, LN,PⅢP and Ⅳ C in patients with chronic hepatitis and hepatic cirrhosis were detected by RIA and compared with the control group. Results The difference of the serum level HA, LN, PⅢP and Ⅳ C in patients with severe hepatitis and hepatic cirrhosis was significant compared with the control group(F=32.4-113.9,q=6.208-23.125,P<0.01). Conclusion The serum level of HA, LN, PⅢP and Ⅳ C may be useful in judging the prognosis for chronic viral hepatitis.

关 键 词：病毒性肝炎 人 肝硬化 血清诊断 HA LN PⅢP Ⅳ-C 

分 类 号：R446.11[医药卫生—诊断学]