rT-PA溶栓治疗急性颈内动脉系统脑梗死  

Thrombolysis with rt-PA for Treatment of Acute Cerebral Infarction in Territory of ICA

作　　者：王少石[1] 杨建道 李威[2] 翟宇 陆勤 石楠 朱宁 严为宏 方晶 金嘉翔 

机构地区：[1]上海第二医科大学附属第九人民医院神经内科,200011 [2]上海市第四人民医院神经内科,200002

出　　处：《中国临床神经科学》2001年第3期259-261,共3页Chinese Journal of Clinical Neurosciences

摘　　要：目的:探讨ｒｔ－ＰＡ治疗发病６ｈ内颈内动脉系统脑梗死的得失。方法:ｒｔ－ＰＡ０．８ｍｇ·ｋｇ－１,低分子肝素、右旋糖酐４０和复方丹参联合应用。结果:３个月后痊愈或基本痊愈７例,预后较好６例,较差２例,死亡６例。死亡病例的初始中风量表(ＳＳＳ)低,脑肿胀严重。死于严重的缺血性脑水肿２例,出血性梗死１例,巨大脑内血肿１例。结论:初始ＳＳＳ越低,预后越差;严重缺血性脑肿胀是导致死亡的值得注意的因素。Aim: To discuss the experience of success and failure about the thrombolysis with rt-PA for treatment of cerebral infacrtion in territory of ICA. Methods:The dose of rt-PA (0.8 mg·kg-1) combined with low molecule heparine, Dextran 40 and Red Sager Root compound. Results: After 3 months, 7 cases obtained with excellent result, 6 cases with good result, 2 cases with poor result, and 6 cases died. Lower baseline SSS and serious cerebral endema appeared in the subgroup of death. 2 cases with serious ischemic edema, 1 case with hemorrhage infarction and one case with large hemotoma were found. Conclusion:The lower baseline SSS was, the worse prognosis happened. It should be paid more attention to that serious ischemic cerebral edema as an important cause of death.

关 键 词：脑梗死 溶栓治疗 RT-PA 急性颈内动脉系统脑梗死 

分 类 号：R743.33[医药卫生—神经病学与精神病学]