潘托拉唑静脉注射治疗上消化道出血的内镜下观察  

The Effect of Pantoprazole on Patients with Upper Gastrointestinal Bleeding Under Endoscope Observation

作　　者：赵晓红[1] 王正[1] 黄杏 

机构地区：[1]宁夏医学院附属医院消化内科

出　　处：《当代医学》2001年第5期46-47,共2页Contemporary Medicine

摘　　要：目的:评价诺森(潘托 拉唑)静脉注射治疗上消化道出血的疗效。方法:对48例上消化道出血病人静脉注射诺森,48h内进行内镜检查判断出血是否停止。失血量少于1000 ml12例诺森40 mg/d;失血量1000 ml-1500 ml 27例,失血量超过1 500ml 9,诺森80 ml/d,连用2d,后改为40 mg/d口服。肝硬化者加用善宁0.2mg/d静滴。全部病例均不应用其他止血药。结果:诺森止血有效率依次是:急性胃粘膜病变100％(8/8),消化性溃疡95.83％(23/24);肝硬化并消化道出血87.5％(14/16)。结论:诺森静脉注射治疗上消化道出血2d疗法内镜下完全止血率93.75％(45/48)。Objective To ev-aluate the effect of Pantoprazole on patients with upper gastrointestinal bleeding. Methods 48 patients vvith upper gastrointestinal bleeding were given Pantoprazole intravenouslv. Endoscopy was carried out within 48 hours for effect judgment. Among the above patients there were 12 subjects which bleeding less than 1000 ml were given Pantoprazole 40mg/d each. There were 27 subjects which bleeding 1000-1500 ml and 9 subjects which bleeding more than 1500 ml were given Pantoprazole 80mg/d each. 2-days intravenous treatment was followed by oral treatrnent. Additional 0.2mg/d Sandostatin was given intravenously to the patient vvith cirrhosis. No other haemostatic was given. Results The effective rate of Pantoprazole vvere 100%(8/8), 95. 83%(23/24) and 87.5%(14/16) for the patients with acute gastric mucosa diseases, gastric ulcer and cirrhosis, respectively. Conclusion The complete stop bleeding rate under endoscope observation was 93.7596 (45/48) carrying out 2-days intravenous Pantoprazole treatment to the patients vvith upper gastrointestinal bleeding.

关 键 词：静脉注射 潘托拉唑 内镜 上消化道出血 Forest判定法 

分 类 号：R573.2[医药卫生—消化系统] R975[医药卫生—内科学]