高能聚焦超声热治疗恶性肿瘤的初步探索附78例治疗临床应用报告  

The Preliminary Study On Malignant Tumors Effects of High Intensive Focused Ultrasound ——A Primary Clinical Report On 78 Cases of Malignant Tumors in HIFU Therapy

作　　者：何申戌[1] 熊六林[1] 于晋生[1] 兰江[1] 

机构地区：[1]北京医科大学北京人民医院,北京100034

出　　处：《中国工程科学》1999年第2期62-66,共5页Strategic Study of CAE

摘　　要：目的　了解HIFU技术治疗癌瘤的临床效果和安全性。方法　应用FEP -BY0 1型高能聚焦超声肿瘤治疗机临床治疗 78例中晚期腹腔、盆腔、多种脏器癌瘤 ,并将全部病例分为空腔脏器和实质脏器癌瘤两大类 ,按各自的标准进行疗效判断 ,并从疼痛、皮肤的灼伤、腔肠出血、穿孔及其它方面进行安全判断。结果　空腔脏器肿瘤 32例 ,出院时 65 6 %肿瘤脱落消失 ,34 4 %萎缩。实质脏器癌瘤 46例 ;治疗后 15 6 %显著疗效 ,80 4 %有效 ,无效 4 3 % (因肋骨阻挡 ) ,与放化疗合用可加速肿瘤脱落或萎缩。结论　HIFU技术对控制肿瘤有肯定疗效 ,并且安全可靠 ,值得推广应用 ;Aim To evaluate the clinical effect and safety of high intensive focused ultrasound(HIFU).Methods 78 cases malignant tumors in abdomen and pelvis were classified into two groups:hollow organic tumors group such as carcinomas of ractum and bladder etc. and solid organic tumors group such as carcinomas of liver and pancreas etc.were treated by FEP BY01 pyrotherapier.The clinical effect was evaluated by different criterion according to their group and the safety was evaluated from painness,skin burning,intestine bleeding,perforation and other aspects.Results In 32 cases of hollow organic tumors,CR(Complete Remission)is 65.6%,PR(Partial Remission)is 34.4% at discharge.In 46 cases of solid organic tumors,marked effect rate is 15.6%,effect rate is 80.4%,and non effect rate is 4.3%(because of ribber stopping ultrasound).HIFU combined with a lower dosage radiotherapy and chemotherapy can speed up tumor falling off or atrophy.Conclusions The HIFU is a kind of safe and effective method to treat abdominal malignant tumor,worth being popularized. [

关 键 词：HIFU 恶性肿瘤 高能聚集超声 热治疗 疗效 

分 类 号：R730.5[医药卫生—肿瘤]