亚砷酸对急性早幼粒细胞白血病患者红细胞系及巨核细胞系的影响  

The effect of arsenons acid on the erythrons and megakaryocytes with acute promyelocytic leukemia.

作　　者：胡宏[1] 魏锦[1] 陈静[1] 王勇[1] 

机构地区：[1]川北医学院附属医院,四川南充637000

出　　处：《四川医学》2001年第8期713-714,共2页Sichuan Medical Journal

摘　　要：目的　探讨亚砷酸对急性早幼粒细胞白血病 (APL)患者红细胞系及巨核细胞系的影响。方法　 11例初治的 APL患者经亚砷酸治疗后观察血象及骨髓象的情况。结果　亚砷酸治疗 2周内血红蛋白及血小板基本无变化 ,随着治疗时间延长红细胞系 3周后、巨核细胞系 4周后则逐渐恢复造血。Objective To investig ate the effects of arsenons acid(AA) on erythrons and megakaryocytes in acute pr omyelocytic leukemia(APL).Methods Analysis on the peripheral and bone ma rrow aspiration smears of 11 patients wi th APL after using AA in the initial tre atment.Results Hemoglobin,3 week s later and platelets,4 weeks later,grad ually recovered to normal after the use of AA in the treatment.Conclusion The use of arsenons acid in the treatm ent of acute promyelocytic leukemia woul d not,on the whole, result in depression of erythrons and megakaryocytes.

关 键 词：急性白血病 早幼粒细胞白血病 巨核细胞系 亚砷酸 诱导分化疗法 

分 类 号：R733.71[医药卫生—肿瘤]