2-甲基取代对吡咯啉-N-氧化物类自旋捕捉剂与超氧阴离子自由基加合物稳定性的影响  

Effect of 2-Methyl Substitution on the Stability of Spin Adducts Composed of Pyrroline-Oxide Analogues and Superoxide Anion Radicals

作　　者：徐英凯[1] 孙健[1] 刘科[1] 陈中伟[1] 张兴康[1] 刘扬[1] 

机构地区：[1]中国科学院化学研究所分子科学中心分子动态和稳态结构国家重点实验室,北京100080

出　　处：《高等学校化学学报》2001年第10期1732-1734,共3页Chemical Journal of Chinese Universities

基　　金：国家重点基础规划项目 (批准号 :G19980 10 10 0 );国家自然科学基金 (批准号 :39890 390 ;39870 2 0 8)资助

摘　　要：The synthesis of a novel α phosphorus containing spin trap, DEPDMPO(5 diethoxy Phosphoryl 2, 5 dimethyl 1 pyrroline \%N\% oxide) and the evaluation of its ability to spin trap the hydroxyl and the superoxide anion radicals were described in the present article. The ability to trap an active superoxide anion radical generated in the photo system Ⅱ(PSII) and the stability of their spin adduct of DEPDMPO as well as three previously reported traps DMPO, DEPMPO and M 3PO were comparatively analyzed according to their chemical structures. In addition, the effects of 2 methyl and \%α\% phosphoryl substituted analogues of DMPO on the stabilities of the corresponding spin adduts were systematicallyThe synthesis of a novel α phosphorus containing spin trap, DEPDMPO(5 diethoxy Phosphoryl 2, 5 dimethyl 1 pyrroline \%N\% oxide) and the evaluation of its ability to spin trap the hydroxyl and the superoxide anion radicals were described in the present article. The ability to trap an active superoxide anion radical generated in the photo system Ⅱ(PSII) and the stability of their spin adduct of DEPDMPO as well as three previously reported traps DMPO, DEPMPO and M 3PO were comparatively analyzed according to their chemical structures. In addition, the effects of 2 methyl and \%α\% phosphoryl substituted analogues of DMPO on the stabilities of the corresponding spin adduts were systematically illustrated

关 键 词：自旋捕捉剂 电子自旋共振 超氧阴离子自由基 加合物 稳定性 2-甲基取代对吡咯啉-N-氧化物 

分 类 号：O626[理学—有机化学] O621.146[理学—化学]