多发性硬化中MRI扫描方法  

Research of MRI scan methods in multiple sclerosis

作　　者：印弘[1] 黄志兰[1] 张贵祥[1] 尤志军[1] 刘满生[1] 赵海涛[1] 

机构地区：[1]第四军医大学西京医院放射诊断科,陕西西安710033

出　　处：《第四军医大学学报》2001年第17期1618-1621,共4页Journal of the Fourth Military Medical University

摘　　要：目的　对照分析不同的扫描方法对多发性硬化(MS)患者的病灶显示程度 ,评价 MR对 MS的分期及预后的诊断价值 .方法　对 2 4例临床确诊的 MS患者行常规及增强MR扫描 ,4例采用抑脂 (Fatsat)序列扫描 ,比较其对 MS斑的显示率及范围 ,并与临床症状进行对照 ,以评价其诊断价值 .结果　 2 4例患者中 ,T1WI显示 MS斑 16个 ,T2 WI显示 MS斑 85个 ,12例增强扫描显示 MS斑 45个 ,4例采用 Fatsat序列增强扫描显示病灶 18个 . T1WI显示 MS斑为略低信号 ,T2 WI显示 MS斑为圆形或卵圆形高信号 ,见于皮层下白质内 ,增强扫描中 ,颅内病灶呈斑片状增强 ,脊髓病灶呈条索或片状增强 ,位于脊髓背及侧方 ,采用 Fatsat序列扫描 ,MS斑呈斑块状增强 ,较 T1WI及 T2 WI病灶大 ,边界清楚 .结论　T2 WI对静止及活动期 MS斑均能较好的显示 ,T1WI仅能部分显示静止期 MS斑 ,增强扫描能较好显示活动期病灶 ,Fat-sat序列较 SE序列能更好显示 MS斑的形态 .MS的临床症状尤其神经损害与AIM To evaluate the diagnostic value of different MRI scan methods in multiple sclerosis. METHODS The plain and enhanced MRI scan was carried out in 24 clinical diagnosed multiple sclerosis, and Fatsat (fat saturation)sequence was used in some cases after enhancement, then the display rate of MS lesion in different methods was compared with the clinical features to evaluate the diagnostic value of different MRI scan methods. RESULTS In 24 cases, there were 16 lesion in T1WI, 85 lesion in T2WI, 18 lesion in 4 cases using Fatsat sequence. The MS lesion was low or isosignal intensity in T1WI, round or ovum high signal intensity in T2WI in white matter. In enhanced scan, the brain lesion was spot like enhancement and the spinal lesion was in the back or lateral side of spinal cord with strip or slice like enhancement. With Fatsat sequence, the MS lesion was clump like enhancement with clearly border, and bigger than that in T1 or T2 weighted image. CONCLUSION The rest and active MS lesion was displayed very well in T2WI. The T1WI can only show MS lesion in rest. The enhanced scan can distinguish active MS lesion while the Fatsat sequence can show MS lesion better than SE sequence. The clinical symptoms and nerve damage of MS have strong relation with MRI appearance. The MRI is the first choice for MS diagnosis. The enhanced scan can show the activity of MS lesion.

关 键 词：多发性硬化 NMR 成像 增强扫描 抑脂 

分 类 号：R744.51[医药卫生—神经病学与精神病学]