婴幼儿腮腺血管瘤中bFGF表达的定量分析及临床意义  

Expression of bFGF in Infant Parotid Gland Hemangioma:Quantitative Analysis and Clinic Importance

作　　者：刘维贤[1] 高原侠[1] 林晓萍[1] 管宇[1] 

机构地区：[1]沈阳中国医科大学附属二院口腔科,110003

出　　处：《口腔医学》2001年第3期115-116,共2页Stomatology

摘　　要：目的 :探讨婴幼儿腮腺血管瘤组织中bFGF与血管瘤生长的关系。方法 :采用免疫组织化学法及图像分析技术。结果 :bFGF在婴幼儿血管瘤中的含量显著多于正常腮腺组织 ;bFGF在血管瘤中幼稚毛细血管周围分布较多。结论 :bFGF在婴幼儿腮腺血管瘤发生、发展过程中起重要作用 ;细胞生物学疗法在对血管瘤治疗方面有较广阔的应用前景。Objective:To determine the relationship between bFGF and growth of infant parotid gland hemangioma.Methods:The immunohistochemical technique and image analysis technique were carried out.The count of bFGF was observed among 40 cases of hemangioma in proliferative stage,30cases in involuting stage,5cases of normal tissue.Results:The bFGF count in infant parotid gland hemangioma was significant higher than which in normal tissue;the bFGF count was the highest in proliferative stage.Conclusion:bFGF made an important role in the proliferative and involuting procession of hemangioma.

关 键 词：婴幼儿 腮腺血管瘤 碱性成纤维细胞生长因子 定量分析 

分 类 号：R739.8[医药卫生—肿瘤] R732.2[医药卫生—临床医学]