四种空管糊剂的抑菌比较研究  

A Study of the Hollow Cancal Paste Therapeutics Potent Bacteriostasis

作　　者：宁放[1] 吴凤云[1] 瞿跃红[2] 

机构地区：[1]上海第二医科大学附属宝钢医院口腔科,201900 [2]上海第二医科大学附属宝钢医院检验科

出　　处：《口腔医学》2001年第3期134-135,共2页Stomatology

摘　　要：目的 :空管糊剂疗法已有 2 0余年历史 ,选材有很大随意性 ,为明确某些配方在治疗中的抑菌作用 ,我们进行了本次实验。方法 :选用强力霉素、甲硝唑、氧氟沙星、地塞米松、甲氧苄啶、愈创木酚、丁香油等组成 4种糊剂 ,对 10 0只离体牙空管封药 ,按不同配药时间放在金黄色葡萄球菌等 5种需氧菌、厌氧菌、兼性菌平皿中进行抑菌实验。结果 :4种糊剂 1周内均有明显的抑菌作用 ,配药 10 0天后仍有一定抑菌作用。结论 :抑菌作用以强力霉素、地塞米松、甲氧苄啶、丁香油糊剂组效果最好。Objective:The hollow canal paste therapeutics has been used clinically for more than 20 years.There is no strict regulation in the selection of proper medication to prepare the paste.In an attempt to compare the bacteristatic effect of common paste prescriptions as filling material.Methods:The author selected 7 drugs to prepare 4 sorts of paste.The 7 drugs are:doxycycline,metronidazole,ofloxacin,dexamethasone,trimethoprim(TMP),guaiacol and clove oil.After a given time of drug dispensation,100 extracted teeth with hollow canal were filled with one of these 4 pastes and were placed onto the media of cultured plates respectively.Five kinds of bacteria including aerobe,anaerobe and facultative anaerobe were inoculated to the cultured plates to evaluate the bacteriostatic effects of the 4 pastes.Obvious bacteriostasis of the 4 pastes was found after a week from paste dispensation.Results:One hundred days after the preparation of the 4 pastes,certain degree of bacteriostatic potency still existed.Conclusion:Among the 4 pastes,those containing doxycycline,dexamethasone,TMP and clove oil showed most potent bacteriostasis.

关 键 词：空管糊剂 离体牙 抑菌值 空管糊剂 根管疗法 

分 类 号：R781.05[医药卫生—口腔医学]