橄榄桥脑小脑萎缩51例临床分析  

Clinical manifestations in olivo-ponto-cerebellar atrophy(51 cases report)

作　　者：邹文[1] 童晓欣[1] 张海鸥[1] 

机构地区：[1]深圳市中心医院神经内科,518036

出　　处：《卒中与神经疾病》2001年第4期230-231,共2页Stroke and Nervous Diseases

摘　　要：目的　分析橄榄桥脑小脑萎缩 (OPCA)的临床表现、CT及MRI特征 ,以利早期诊断。方法　对 5 1例OPCA病人的临床表现及其 18例头颅CT和 33例头颅MRI特征进行回顾性分析。结果　OPCA男性多于女性 ,平均年龄 45 .5岁 ,平均病程 12年。其临床表现多种多样 ,以小脑症状、植物神经症状及锥体外系症状多见 ,头颅MRI比头颅CT效果好 ,以小脑和脑干萎缩为主 ,大脑皮质萎缩轻。结论　成年人出现小脑性共济失调、植物神经功能紊乱和锥体外系症状 ,应高度怀疑OPCA ,且MRI有助于早期诊断。Objective To analyze the clinical manifestations, CT scans and MRI images in the early diagnosis of olivo ponto cerebellar atrophy(OPCA). Methods 51 patients with OPCA were retroactively studied. Results The average age of patients was 45.5 years old and male was more than female. The clinical manifeslations varies, in which the most important ones were cerebellar ataxia, autonamic nerve deficit and extrapyramidal symptom. MRI showed obviousatrophy in cerebellum and brain stem and less in cerebral cortex. Conclusion The adults who had cerebellar ataxia, autonamic nerve disturbance and extrapyramidal symptoms should have the possibility of OPCA. MRI may play an important role in the early diagnosis.

关 键 词：橄榄桥脑小脑萎缩 OPCA 临床表现 MRI CT 预后 

分 类 号：R742.82[医药卫生—神经病学与精神病学]