卒中后抑郁状态及其影响因素的相关研究  

A study of prevalence and related factors of post-stroke depression

作　　者：龙洁[1] 蔡焯基[2] 刘永珍[3] 柴滨[1] 贺佳丽[2] 任艳萍[2] 王涛[4] 牛世芹[4] 余华峰[5] 刘艳[5] 魏明 王丽[6] 王效敏[7] 李菁[7] 李冬华[8] 蒋初明[8] 金鑫[9] 王友兰[10] 陈黔妹[10] 于小千 刘力[3] 王得新[11] 康智敏[11] 张茁[12] 张菁[12] 唐启盛 韩刚 

机构地区：[1]北京天坛医院,北京100050 [2]北京安定医院 [3]北京海淀医院 [4]北京朝阳医院 [5]北京同仁医院 [6]北京和平里医院 [7]北京铁路总医院 [8]航天部711医院 [9]北京复兴医院 [10]北京酒仙桥医院 [11]北京友谊医院 [12]北京东方医院 [13]北京安贞医院

出　　处：《中国神经精神疾病杂志》2001年第6期430-432,共3页Chinese Journal of Nervous and Mental Diseases

基　　金：北京市科委资助课题(编号:953304005)

摘　　要：目的 研究北京市卒中患者伴发卒中后抑郁状态（ＰＳＤ）的发生率和相关因素。方法 采用Ｈａｍｉｌｔｏｎ抑郁量表、ＳＤＳ抑郁自评量表和自制一般情况调查表，对北京市 ７个区 １２家医院的 １９６６例卒中患者进行测查，并用Ｌｏｇｉｓｔｉｃ回归分析法对３３种相关因素进行分析。结果ＰＳＤ总发生率为３５．０％，其中轻度２２．５％、中度９．３％、重度3．２％。影响ＰＳＤ发生的相关因素依次是既往抑郁症史、近期负性生活事件、家庭关系、性别、病灶数目、合并疾病种类、护理人员和病灶前后部位。结论 ＰＳＤ发生率较高，它可能是社会心理学因素和神经生物学因素共同作用的结果。Objective To investigate the prevalence and related factors of post-stroke depression(PSD). Methods 1966 patients with stroke were assessed by Hamiton Depression Rating Scales(HAMD), Self-Rating Depression Scale(SDS), and a self-designed questionaire. A multiple factor analysis with the logistic regression method was carried out to analysis 33 related fac- tors in these data. Results Among them, 688 cases(35.0%) were identified as suffering from depression, of which 22.5%, suffered from mild depression middle 9.3% suffered from moderate depression and 3.2% severe depression. In addition, the step- wise regression analysis showed that important risk factors of PSD included history of depression, negative life accidents, family hannony, sex, number of lesions, complication, caregivers and lesion location. Conclusions The prevalence of PSD is high, and it may he caused by both psychosocial and neurobiological factors.

关 键 词：卒中后抑郁 发生率 危险因素 研究 

分 类 号：R749.13[医药卫生—神经病学与精神病学]