放射性血管支架制备研究进展  

Preparation of radioactive endovascular stent

作　　者：张晓东[1] 李文新[1] 

机构地区：[1]中国科学院上海原子核研究所,上海201800

出　　处：《核技术》2001年第11期946-951,共6页Nuclear Techniques

基　　金：上海市浦东种子基金 (PKZ990 3)

摘　　要：综述了用于预防PTCA后血管再狭窄的放射性血管支架的各种制备方法 :同位素离子注入法、活化法及直接表面沉积或涂覆法的研究进展 ,分析了各种方法的特点 ,简述各种放射性支架的应用情况 。Radioactive stents is a promising avenue to reduce the rate of restenosis after percutaneous transluminal coronary angioplasty (PTCA). In this paper, the preparation methods of radioactive stents including ion implantation, activation in reactor or in cyclotron and surface handling methods were reviewed. Ion implantation was used to produce the 32 P-implanted stent undergoing clinic evaluation. Other methods also showed their respective advantages. The composit polymer stent or nitinol stent may be the next aims to be explored in this field.

关 键 词：PTCA 放射性血管支架 离子注入 活化 表面沉积 心肌梗塞 治疗 血管再狭窄 放射性治疗 

分 类 号：R817.52[医药卫生—影像医学与核医学]