肝豆状核变性患者合并胆囊异常及相关因素的研究  

A study on gallbladder disorders and correlated factors in patients with hepatolenticular degeneration

作　　者：洪铭范[1] 吕达平[1] 苏增峰[1] 李凯[1] 胡纪原[1] 杨任民[1] 

机构地区：[1]安徽中医学院神经病学研究所,合肥230031

出　　处：《中国实用内科杂志》2001年第11期653-654,共2页Chinese Journal of Practical Internal Medicine

基　　金：国家自然科学基金资助课题 (No .395 70 878)

摘　　要：目的　研究肝豆状核变性 (HLD)患者并发胆囊异常及其相关因素。方法　对 2 0 0例HLD患者行胆囊B超检查 ,详细记录相关病史、症状、体征及临床分型 ,并分析其间的关系。结果　 2 0 0例患者中 82例经B超检查发现胆囊异常 ( 4 1 0 0 % ) ,主要表现为胆囊壁增厚、胆囊增大、慢性胆囊炎或胆囊结石等。临床分析表明 82例胆囊异常中仅 17例有胆囊疾病症状 ;胆囊异常与年龄、性别无关 ,而与早期肝症状及临床分型有关。结论　HLD患者往往并发胆囊异常 ,以具有早期肝症状及肝 -脑型的患者更为多见 。Objective To investigate the abnormality of gallbladder and related factors in the patients with hepatolenticular degereration (HLD).Methods 200 patients were screened by B-type ultrasonography.The relations of the abnormality of gallbladder and the clinical materials were analyzed.Results The B-type hepatobiliary ultrasonography revealed the thicking wall of enlarge of gallbladder,chronic cholecystitis or cholelithias is in 82 patients (41 percent).Among these patients,only 17 patients showed symptoms of cholecystitis or cholelithiasis.The abnormality of gallbladder was related to the history of liver damage and clinical types of disease.Conclusion The patients with HLD often have pathological changes of gallbladder.Hepatobiliary ultrasonography must be regarded as a routine examination to HLD.

关 键 词：肝豆状核变性 胆囊异常 并发症 HLD B超 

分 类 号：R742.4[医药卫生—神经病学与精神病学] R657.4[医药卫生—临床医学]