输精管绝育术与人群恶性肿瘤死亡率的关系  

EFFECT OF VASECTOMY ON MORTALITY FROM MALIGNANT TUMOR IN MEN

作　　者：左惠娟[1] 姚玉红[2] 张思霖[3] 陈彬[2] 王安荣[4] 黄强[3] 邹平[3] 秦健[3] 

机构地区：[1]北京心肺血管疾病研究所,100029 [2]华西医科大学公共卫生学院 [3]四川省计划生育科学研究所 [4]四川省肿瘤研究所

出　　处：《现代预防医学》2001年第4期423-425,共3页Modern Preventive Medicine

摘　　要：目的 :探讨输精管绝育术与恶性肿瘤死亡率的关系。方法 :采用三年一次性回顾结合两年随访调查的历史前瞻方法 ,收集四川盐亭县 40～ 70岁男性的绝育及死亡等资料 ,比较绝育与未绝育人群恶性肿瘤死亡率。结果 :绝育人群恶性肿瘤死亡危险低于未绝育组 ,标化死亡率分别为 7.0 1‰、 5 .5 3‰ (u=2 .5 3,P<0 .0 5 ) ,年龄调整 SMR=0 .88(95 %CI:0 .88- 0 .96 )。并且 ,食管癌、肝癌死亡危险也显著降低 ,年龄调整 SMR分别为 0 .78(95 %CI:0 .6 7- 0 .88)、 0 .76 (95 %CI:0 .5 7- 0 .94)。绝育人群中 ,绝育时年龄与绝育年限在恶性肿瘤死亡中存在相乘模式的交互作用。结论 :输精管绝育术不增加人群恶性肿瘤死亡率。Objective:In order to discuss the relationship between vasectomy and malignant tumor.Methods:The mortality of vasectomized men was compared with that of non-vasectomized men aged from 40 to 70 years old in Yanting county Sichuan Province using the method of three-year retrospective and two-year follow up survey.Results:The death risk of vasectomized men was lower significantly than that of non-vasectomized men,the standardized mortality was 7.01‰ and 5.53‰(u=2.53,P<0.05).SMR(adjusted by age) was 0.88(95%CI:0.81-0.96).A decreased death risk of esophageal and liver cancer was found,the SMR was 0.78(95%CI:0.67-0.88),0.76(95%CI:0.57-0.94).Conclusion:Showed result the death risk was not increased by vasectomy.

关 键 词：输精管绝育术 恶性肿瘤 标化死亡率 标准化死亡比 

分 类 号：R730.2[医药卫生—肿瘤] R169[医药卫生—临床医学]