难治性鼻咽癌处理策略——附307例分析  

The Strategy of Treatment for Refractory Nesopharyngeal Carcinoma:Attend 307 Cases Analysis

作　　者：陈平[1] 胡金香[2] 曹凤军[1] 类健翔[1] 汤翠菊[1] 李林钧[1] 

机构地区：[1]十堰市人民医院肿瘤中心,湖北十堰442000 [2]武汉大学中南医院,湖北武汉430071

出　　处：《肿瘤防治杂志》2001年第5期497-499,共3页China Journal of Cancer Prevention and Treatment

摘　　要：目的 :对难治性鼻咽癌治疗策略进行探讨。方法 :按鼻咽局灶残留和复发 (包括颈部 )分成二组 ,统计经治后各组生存结果 ,对复发部位、疗程、间隔、治疗方法进行逐一对比分析。结果 :鼻咽癌根治性外照后局灶残留腔内后装剂量追加 (称Ⅱ组 )和复发性鼻咽癌 (称Ⅰ组 )经治后 5年生存率分别为 4 4 8%和2 7 3% (P <0 0 1)。远处转移和颅 (底骨 )神经损伤 ,分别为二组主要死因。结论 :鼻咽癌首程根治成功是获长期生存的关键 ,一旦复发再治 ,生存结果明显降低 ,如若处置恰当 ,其疗效并非一定是姑息性的。Objective The current study was designed to explore the strategy of treatinert for Nesopharyngeal Carcinoma.Methods 307 patients were divided into two groups according to nesopharyngeal residue and local recurrence (including cervical lymph nodes metastasis) , we made statistics of two groups survival results and compared with recurrent location, course of treatment, interval and therapy methods, respectively.Results We named local residue which be added Intracavitary Afterloading Irradiation after curative External irradiation asⅡgroup and named recurrent Nesopharyngeal Carcinoma as Ⅰgroup.The 5 year survial rates were 44 8% and 27 3%.respectively( P <0 01).Distant metastasis and injure to cranial nurves were the main causes of death.Conclusion The success of Nesopharyngeal Carcinoma's first cruaty is the crux to survive long term. Once tumor recur and etherapy, the survial rate reduced significantly. But if it be proper treated,the effect is not single palliative.

关 键 词：鼻咽癌 难治性 治疗 

分 类 号：R739.63[医药卫生—肿瘤]