^(201)Tl显像在乳腺包块鉴别诊断中的应用  

Imaging of ^(201) Thallium in differential diagnosis of breast mass

作　　者：汪静[1] SangKyunBAE 

机构地区：[1]第四军医大学西京医院核医学科,陕西西安710033 [2]韩国釜山Kosin大学医学院核医学科

出　　处：《第四军医大学学报》2001年第13期1233-1235,共3页Journal of the Fourth Military Medical University

摘　　要：目的　评价放射性核素2 0 1 Tl显像在协助诊断与鉴别诊断乳腺包块中的临床应用 .方法　对 3 1例经病理证实的乳腺包块患者均行 2 0 1 Tl显像 ( 74～ 111MBq) ,同时与病理结果进行对比 .结果　 11例乳腺恶性包块中 ,2 0 1 Tl检测出 10例(灵敏度 90 .9% ) ,检出包块最小直径为 1.5 cm,其中 1例假阴性系包块过小且已接受多次化疗所致 .另外 2 0例乳腺良性病例中 ,17例无 2 0 1 Tl摄取 (特异性 85 .0 % ) ,3例纤维囊性病变也有 2 0 1 Tl的摄取 .2 0 1 Tl显像诊断与鉴别诊断乳腺包块的准确率为 87.1% .结论　 2 0 1 Tl显像有望成为临床上广泛应用的一种有效、简便的鉴别诊断乳腺包块性质的方法 .AIM To evaluate clinical efficiency of thallium 201 scanning as a potential test in differentiating malignant from benign lesions of the breast. METHODS Thirty one women with breast mass proved by biopsy underwent thallium 201 scanning of the breast (iv. 74~111 MBq), compared with the biopsy results of its anterior and lateral images. RESULTS Of 11 patients with breast cancers, 10 cases (sensitivity 90.9%) were detected, the smallest detectable cancer being 1.5 cm in diameter. One patient who had received several cycles of chemotherapy did not show thallium uptake. There was no thallium accumulation in breast mass of 17 of 20 patients with benign lesions (specificity 85.0%). Three fibrocystic cases showed relative thallium uptake in their breast mass. The accuracy of breast mass diagnosis by thallium scanning was 87.1%. CONCLUSION Thallium scanning has proved to be an easy and effective test in clinical practice in differentiating malignant from benign lesions of the breast.

关 键 词：铊 乳腺癌 鉴别诊断 铊201 放射性核素显像 

分 类 号：R737.9[医药卫生—肿瘤] R730.44[医药卫生—临床医学]