银汞合金对变链菌生长抑制作用的体内研究  

Influence of amalgam on the growth of Streptococcus mutans:An in vovo study

作　　者：汪俊[1] 刘正[1] 

机构地区：[1]上海第二医科大学附属第九人民医院儿童口腔科,200011

出　　处：《实用口腔医学杂志》2001年第6期502-504,共3页Journal of Practical Stomatology

摘　　要：目的 :研究银汞合金体内抗菌活性。方法 :定期采取实验者 (16名 )新银汞合金充填体表面菌斑 ,而陈旧性银汞合金充填体 (>3年 )者 (14名 )充填体表面菌斑仅采样一次 ,检测陈旧性银汞合金充填体和新银汞合金充填体表面菌斑中变链菌的检出率及 CFU。结果 :银汞合金充填后 8周内 ,银汞合金充填体表面菌斑中变链菌的 CFU与对照组比较 ,差异均有显著性。而陈旧性银汞合金充填体表面菌斑中变链菌的与对照组比较 ,差异无显著性。结论 :银汞合金充填体在体内显示了一定的抑菌活性。Objective:To study the antibacterial activity of dental amalgam against S.mutans in vivo.Methods:Plaque samples were collected from amalgam surface 1 d,1,2,4 and 8 weeks after tooth restoration with amalgam( group of fresh amalgam) in 16 subjects and from anothor 14 subjects with amalgam tooth restoration for more than 3 years (group of aged amalgam).Plaque samples were collected only once.Isolation frequency (IF) and colony forming unite(CFU) of S.mutans were tested.The plague samples from oposite tooth were used as the controls.Results:In the group of fresh amalgam IF and CFU of S.mutans were heigher on amalgam than on the control teeth(P<0.05) until 8 weeks after restoration,while in the group of aged amalgam those were not significantly different (P>0.05).Conclusion:Amalgams may have inhibitory effects on the growth of S.mutans.

关 键 词：银汞合金 变链菌 体内 生长抑制 

分 类 号：R780.2[医药卫生—口腔医学]