西沙必利促慢性肝炎患者胆囊排空的疗效观察  

Gallbladder emptying in patients with chronic hepatitis:improvement of gallbladder motility with cisapride

作　　者：程天明[1] 高方[2] 周华[3] 袁爱力[1] 

机构地区：[1]第一军医大学南方医院全军消化病研究所,广东广州510515 [2]第一军医大学南方医院内分泌科,广东广州510515 [3]第一军医大学南方医院超声科,广东广州510515

出　　处：《中国医学物理学杂志》2001年第4期254-255,共2页Chinese Journal of Medical Physics

摘　　要：目的:了解西沙必利促进慢性肝病患者胆囊排空情况。方法:超声对比观察22例正常对照者及30例慢性肝病患者空腹胆囊大小及脂肪餐后胆囊收缩情况。对其中16例有胆囊排空障碍的病人,给予西沙必利10mg,3/日治疗四周后复查。结果:正常对照组与慢性肝病组餐前胆囊面积有显著差异,餐后胆囊收缩率也有显著差异,慢性肝炎组存在餐后胆囊排空障碍。16例有排空障碍的慢性肝病患者经西沙必利治疗4周后,胆囊排空有显著改善。结论:慢性肝病患者常伴有胆囊排空运动障碍,西沙必利有改善胆囊排空障碍的作用。Objective:To study gallbladder emptying in patients with chronic hepatitis(CH)and to know whether cisapride can improve it.Methods:Ultrasonography(US)findings of the fasting gallbladder and after fatty meal in22normal volunteers and30patients with chronic hepatitis were studied.Sixteen patients with disorders of gallbladder empty were treated with cisapride.Four weeks later the contractile rates of gallbladder were evaluated by US again.Results:The CH patients had high rates of thicken gallbladder wall and gallbladder sludge than normal volunteers.The contractial rate in30minutes after fatty meal of CH patients were16.53±4.30compared to39.80±5.50in normal volunteers.Four weeks later been treated with cisapride,the contractile rates of gallbladder in the16patients were29.75±6.41compared to16.53±4.30before treated.Conclusion:There were disorders of gallbladder emptying in patients with chronic hepatitis,and cisapride seems to be useful to improve it.

关 键 词：慢性肝炎 胆囊运行 西沙必利 

分 类 号：R575.6[医药卫生—消化系统] R512.62[医药卫生—内科学]