缺血性中风患者测定血浆D-二聚体水平的意义  

Significance of detecting serum D-dimer in patients with ischemic stroke

作　　者：林锦祥[1] 沈敏海[1] 

机构地区：[1]福建省龙岩市第一医院,福建龙岩364000

出　　处：《心血管康复医学杂志》2001年第6期508-510,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的 :探讨血浆 D-二聚体水平与不同时相、不同面积缺血性中风患者的关系。方法 :采用胶乳凝聚法按不同年龄组分别测定 92例正常人和 118例缺血性中风患者急性期和恢复期血浆中的 D-二聚体含量。结果 :缺血性中风患者急性期及恢复期血浆 D-二聚体的含量均较正常对照组明显升高 (P<0 .0 0 1) ,以急性期最高 ,恢复期 D-二聚体含量已出现下降 ,与急性期相比有显著性意义 (P<0 .0 5 ) ,但仍明显高于正常对照组 (P<0 .0 5 )。并且与梗死面积呈正相关 ;正常人 D-二聚体含量随年龄的增高有增长的趋势 ,低年龄组与高年龄组有显著性差异 (P<0 .0 1)。结论 :缺血性中风患者急性期确实存在高凝状态 ,血浆 D-二聚体水平不仅可作为观察缺血性中风病情轻重的指标 ,而且也是判断预后、观察治疗效果的监测指标之一。Objective:To explore the significance of detecting serum D\|dimer in patients with ischemic stroke.Methods:Detect serum D\|dimer level by latex agglutination in 92 normal controls(divide to <50,51~65,>65 age 3 groups) and 118 patients with ischemic stroke(divide to acute and convalescent period).Results:D\|dimer levels increased associated with age increase.Compared with <50 age group,D\|dimer levels significantly increased in >65 age group( P <0 01).Compared with control group D\|dimer levels significantly increased in ischemic strode(acute and convalescent period),its P was <0 001,but D\|dimer level was higher in acute period compared with convalescent period( P <0 05).Conclusion:Level of serum D\|dimer obviously increase in patients with ischemic stroke,it may be used for index of stratification and predicting prognosis.

关 键 词：缺血性中风 D-二聚体 胶乳凝聚法 

分 类 号：R743.3[医药卫生—神经病学与精神病学]